Browsing Administrative Staff Authors by Subject "Cancer"
Now showing items 1-11 of 11
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Evaluation of an e-Learning teaching innovation to assist clinical radiation therapy educators in the provision of student feedback
(2021)Background: Clinical placement is an integral part of the Radiation Therapy undergraduate programme. Feedback and formative assessment during clinical placement are regarded as key to developing clinical skills and ... -
Generation and characterisation of Cisplatin-resistant non-small cell lung cancer cell lines displaying a stem-like signature.
(2013)Introduction: Inherent and acquired cisplatin resistance reduces the effectiveness of this agent in the management of non- small cell lung cancer (NSCLC). Understanding the molecular mechanisms underlying this process ... -
Nanomedicine applied to translational oncology: A future perspective on cancer treatment.
(2016)The high global incidence of cancer is associated with high rates of mortality and morbidity worldwide. By taking advantage of the properties of matter at the nanoscale, nanomedicine promises to develop innovative drugs ... -
Polymer-Stabilized Elemental Boron Nanoparticles for Boron Neutron Capture Therapy: Initial Irradiation Experiments
(2022)Sufficient boron-10 isotope (10B) accumulation by tumor cells is one of the main requirements for successful boron neutron capture therapy (BNCT). The inability of the clinically registered 10B-containing borophenylalanine ... -
The presentation of metabolic dysfunction and the relationship with energy output in breast cancer survivors: a cross-sectional study.
(2013)Background Breast cancer prognosis can be adversely influenced by obesity, physical inactivity and metabolic dysfunction. Interventions aimed at improving surrogate markers of breast cancer risk such as insulin resistance ... -
The prevalence of alpha-1 antitrypsin deficiency in Ireland
(2011)Background: Alpha-1 antitrypsin deficiency (AATD) results from mutations in the SERPINA1 gene and classically presents with early-onset emphysema and liver disease. The most common mutation presenting with clinical evidence ... -
A prospective study of circulating mutant KRAS2 in the serum of patients with colorectal neoplasia: strong prognostic indicator in postoperative follow up
(2003)BACKGROUND AND AIMS: Mutant tumour derived DNA has been detected in the sera of colorectal cancer patients. We investigated if mutant serum KRAS2 was detectable preoperatively in a large group of patients with colorectal ... -
A Spheroid Model of Early and Late-Stage Osteosarcoma Mimicking the Divergent Relationship between Tumor Elimination and Bone Regeneration
(2021)Osteosarcoma is the most diagnosed bone tumor in children. The use of tissue engineering strategies after malignant tumor resection remains a subject of scientific controversy. As a result, there is limited research that ...