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dc.contributor.authorGARAVAN, HUGH PATRICK
dc.date.accessioned2008-11-19T14:10:51Z
dc.date.available2008-11-19T14:10:51Z
dc.date.issued2006
dc.date.submitted2006en
dc.identifier.citationChambers, C. D., Bellgrove, M. A., Stokes, M. G., Henderson, T. R., Garavan, H., Robertson, I. H., & Mattingley, J. B. `Executive `brake failure? following deactivation of human frontal lobe? in Journal of Cognitive Neuroscience, 18, (3), 2006, pp 444 - 455en
dc.identifier.otherY
dc.identifier.urihttp://hdl.handle.net/2262/24799
dc.descriptionPUBLISHEDen
dc.description.abstractIn the course of daily living, humans frequently encounter situations in which a motor activity, once initiated, becomes unnecessary or inappropriate. Under such circumstances, the ability to inhibit motor responses can be of vital importance. Although the nature of response inhibition has been studied in psychology for several decades, its neural basis remains unclear. Using transcranial magnetic stimulation, we found that temporary deactivation of the pars opercularis in the right inferior frontal gyrus selectively impairs the ability to stop an initiated action. Critically, deactivation of the same region did not affect the ability to execute responses, nor did it inf luence physiological arousal. These findings confirm and extend recent reports that the inferior frontal gyrus is vital for mediating response inhibition.en
dc.format.extent444en
dc.format.extent455en
dc.format.extent638772 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.publisherMIT Pressen
dc.relation.ispartofseriesJournal of Cognitive Neuroscienceen
dc.relation.ispartofseries18en
dc.relation.ispartofseries3en
dc.rightsYen
dc.subjectPsychologyen
dc.titleExecutive `brake failure? following deactivation of human frontal lobeen
dc.typeJournal Articleen
dc.type.supercollectionscholarly_publicationsen
dc.type.supercollectionrefereed_publicationsen
dc.identifier.peoplefinderurlhttp://people.tcd.ie/garavanh


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