Pharmacy and Pharmaceutical Sciences (Theses and Dissertations)
Recent Submissions
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The treatment of obesity using magneto -mechanical effect
Obesity is a very prevalent condition that can be very often associated with the development of comorbidities, such as insulin resistance, hypertension, and hyperlipidaemia that can lead to cardiovascular and cerebrovascular ... -
A mixed-methods approach to explore the association between age and medication -related problems among adults
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2024)General introduction Much attention was focused on the ageing phenomenon and how to improve the quality of life in older people. Medication-related problems (MRPs) can potentially lead to hospital admissions, increased ... -
A theory-based exploration of the medicines management process provided to older people residing in the nursing home setting in the Republic of Ireland
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Introduction While the population is ageing globally, this does not necessarily mean that they are living healthier. The multimorbidity and polypharmacy in the older population (age> 65 years) increases their risk of ... -
Improving appropriate polypharmacy in older people in primary care
Introduction People are living longer but not necessarily in better health. The ageing population coupled with the increasing prevalence of chronic conditions has resulted in many older people being prescribed polypharmacy ... -
Enantioseparation and structural optimisation of b-lactams and stilbene analogues for the treatment of triple negative breast and chemoresistant colorectal cancers
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Triple negative breast cancer (TNBC) is characterised by an extremely aggressive clinical phenotype and minimal expression of typical breast cancer receptors such as the estrogen, progesterone or HER2 receptors.1, 2 Patient ... -
Characterisation of Depressive Symptoms in Huntington's Disease and of the Pharmacological Treatment for Depression: patterns, trends and Statistical Analysis of Enroll-HD Dataset
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2022)Background: Huntington?s Disease (HD) is a rare autosomal dominant genetic disorder characterised by a triad of motor, psychiatric and cognitive symptoms. Among the psychiatric manifestations, depression is very common and ... -
Patterns of Medication Use Associated with Epilepsy and Comorbid Behavioural and Mental Disorders in Older People with Intellectual Disability
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2022)Background: There is increasing concern worldwide regarding the levels of use and suboptimal prescribing of psychotropic medication in people with intellectual disability. Antipsychotics, in particular are often prescribed ...