Browsing School of Biochemistry & Immunology by Sponsor "GlaxoSmithKline"

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  • Characterization of Staphylococcal protein A cellular interactions to facilitate its development as a vaccine antigen 

    Fox, Proinnsias Garoid (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
    The development of a vaccine from bench to bedside is a lengthy and complex process, which is so rarely fully realized and followed throughout. During the course of this project, we have been able to follow the development ...

  • Malonylation of GAPDH in the inflammatory response in macrophages 

    GALVAN-PENA, SILVIA (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2018)
    Succinylation and malonylation are two recently discovered protein post-translational modifications. They involve the attachment to lysines of metabolism-derived succinyl and malonyl groups respectively, resulting in a ...

  • NLRP1 drives inflammasome responses in the human respiratory epithelium 

    Lam, Nathaniel Laurence (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)
    The airway epithelium is now considered crucial to the orchestration of respiratory inflammatory responses and tissue remodelling. It functions as the first line of defence against inhaled concomitants and coordinates the ...