Browsing School of Biochemistry & Immunology by Sponsor "European Union (EU)"
Now showing items 1-17 of 17
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A non-toxic, reversibly released imaging probe for oral cancer that is derived from natural compounds.
(2021)CD44 is emerging as an important receptor biomarker for various cancers. Amongst these is oral cancer, where surgical resection remains an essential mode of treatment. Unfortunately, surgery is frequently associated with ... -
Raising the bar in anticancer therapy:recent advances in, and perspectives on, telomerase inhibitors
(2019)Telomerase is a ribonucleic reverse transcriptase enzyme that uses an integral RNA component as a template to add tandem telomeric DNA repeats, TTAGGG, at the 3′ end of the chromosomes. 85–90% of human tumors and their ... -
Spiroindoline-Capped Selective HDAC6 Inhibitors: Design, 2 Synthesis, Structural Analysis, and Biological Evaluation
(2020)Histone deacetylase inhibitors (HDACi) have emerged as promising therapeutics for the treatment of neurodegeneration, cancer, and rare disorders. Herein, we report the development of a series of spiroindoline-based HDAC6 ...