Browsing School of Biochemistry & Immunology by Title
Now showing items 1007-1015 of 1015
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The Warburg effect then and now: From cancer to inflammatory diseases
(2013)Inflammatory immune cells, when activated, display much the same metabolic profile as a glycolytic tumor cell. This involves a shift in metabolism away from oxidative phosphorylation towards aerobic glycolysis, a phenomenon ... -
Worsening Cognitive Impairment and Neurodegenerative Pathology Progressively Increase Risk for Delirium.
(2015)Background Delirium is a profound neuropsychiatric disturbance precipitated by acute illness. Although dementia is the major risk factor this has typically been considered a binary quantity (i.e., cognitively impaired ... -
Would hemodialysis patients benefit from a Staphylococcus aureus vaccine?
(2019)Staphylococcus aureus bloodstream infection can have potentially catastrophic consequences for patients on hemodialysis. Consequently, an effective vaccine to prevent S aureus infection would have a significant influence ... -
X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex
(2016)Serial femtosecond X-ray crystallography (SFX) using an X-ray free electron laser (XFEL) is a recent advancement in structural biology for solving crystal structures of challenging membrane proteins, including G-protein ... -
α-Lactalbumin-oleic acid complex : structure function dynamics
(Trinity College (Dublin, Ireland). School of Biochemistry and Immunology, 2015)Human alpha-lactalbumin made lethal to tumor cells (HAMLET) and its analogues are partially unfolded protein-oleic acid complexes that exhibit selective tumoricidal activity normally absent in the native protein itself, ... -
β-Defensins: Farming the microbiome for homeostasis and health
(2019)Diverse commensal populations are now regarded as key to physiological homeostasis and protection against disease. Although bacteria are the most abundant component of microbiomes, and the most intensively studied, the ... -
γδ T cells and NK cells – Distinct Pathogenic Roles as Innate-Like Immune Cells in CNS Autoimmunity.
(2015)Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease that affects the central nervous system (CNS) resulting in progressive cognitive decline and physical disability. Experimental autoimmune encephalomyelitis ...
