Browsing Mechanical & Manufacturing Eng (Scholarly Publications) by Sponsor "European Research Council (ERC)"
Now showing items 1-20 of 22
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Cell-matrix interactions regulate mesenchymal stem cell response to hydrostatic pressure
(2012)Both hydrostatic pressure (HP) and cell-matrix interactions have independently been shown to regulate the chondrogenic differentiation of mesenchymal stem cells (MSCs). The objective of this study was to test the hypothesis ... -
Collagen fibre characterisation in arterial tissue under load using SALS
(2017)The collagen fibre architecture of arterial tissue is known to play a key role in its resultant mechanical behaviour, while maladaptive remodelling of this architecture may be linked to disease. Many of the techniques ... -
Cyclic Hydrostatic Pressure Promotes A Stable Cartilage Phenotype And Enhances The Functional Development Of Cartilaginous Grafts Engineered Using Multipotent Stromal Cells Isolated From Bone Marrow And Infrapatellar Fat Pad.
(2014)The objective of this study was to investigate how joint specific biomechanical loading influences the functional development and phenotypic stability of cartilage grafts engineered in vitro using stem/progenitor cells ... -
Determination of two-dimensional space-time correlations in jet flows using simultaneous PIV and LDV measurements
(2010)The two-dimensional space-time turbulence statistics of free shear jet flows in the form of the two-point velocity correlation tensor are important for aeroacoustic noise source modelling based on the acoustic analogy ... -
Diffusion tensor imaging and arterial tissue: establishing the influence of arterial tissue microstructure on fractional anisotropy, mean diffusivity and tractography
(2021)In this study we investigated the potential of diffusion tensor imaging (DTI) for providing insight into microstructural changes in arterial tissue by exploring the influence that cell, collagen and elastin content have ... -
Expansion in the presence of FGF-2 enhances the functional development of cartilaginous tissues engineered using infrapatellar fat pad derived MSCs
(2012)MSCs from non-cartilaginous knee joint tissues such as the infrapatellar fat pad (IFP) and synovium possess significant chondrogenic potential and provide a readily available and clinically feasible source of chondroprogenitor ... -
Experimental Investigations of Coherence Based Noise Source Identification Techniques for Turbomachinery Applications - Classic and Novel Techniques (AIAA-2011-2830)
(2011)Coherence based noise source identi cation techniques utilise the ordinary linear coherence function between two signals to identify the contribution of one or more sources to the noise measured at a location of interest. ... -
Mechanically stimulated osteocytes promote the proliferation and migration of breast cancer cells via a potential CXCL1/2 mechanism
(2021)Bone represents the most common site for breast cancer metastasis. Bone is a highly dynamic organ that is constantly adapting to its biophysical environment, orchestrated largely by the resident osteocyte network. Osteocytes ... -
The pericellular environment regulates cytoskeletal development and the differentiation of mesenchymal stem cells and determines their response to hydrostatic pressure.
(2013)The objective of this study was to examine the interplay between matrix stiffness and hydrostatic pressure (HP) in regulating chondrogenesis of mesenchymal stem cells (MSCs) and to further elucidate the mechanotransductive ...