Browsing Mechanical & Manufacturing Eng (Theses and Dissertations) by Subject "tissue engineering"

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  • 3D bioprinting of cartilage-mimetic implants for biological joint resurfacing 

    SCHIPANI, ROSSANA (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)
    A major challenge in the field of tissue engineering and regenerative medicine is the development of effective therapies for treating large cartilage or osteochondral defects and ultimately regenerating whole osteoarthritic ...

  • Development and characterization of corneal substitutes from decellularized tissues 

    Fernández Pérez, Julia (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)
    Diseases affecting the cornea can lead to vision impairment and ultimately to blindness. It is estimated that 45 million people worldwide suffer from corneal blindness. Rejection in high-risk patients and donor shortage ...

  • Development of mechanobiomimetic strategies to drive stem cell behaviour for bone regeneration 

    EICHHOLZ, KIAN (Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)
    There are a host of cases where clinical intervention must be taken to treat diseased or damaged bone, including severe fractures, defects, tumours requiring tissue removal, and debilitating diseases such as osteoporosis. ...