Browsing Dental Science (Scholarly Publications) by Title
Now showing items 46-54 of 54
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The role of the Mediator complex in fungal pathogenesis and response to antifungal agents.
(2023)Mediator is a complex of polypeptides that plays a central role in the recruitment of RNA polymerase II to promoters and subsequent transcriptional activation in eukaryotic organisms. Studies have now shown that Mediator ... -
A Ser29Leu SUBSTITUTION IN THE CYTOSINE DEAMINASE Fca1p IS RESPONSIBLE FOR CLADE-SPECIFIC 5-FLUCYTOSINE RESISTANCE IN Candida dubliniensis
(2009)The population structure of the opportunistic yeast pathogen Candida dubliniensis is composed of three main multilocus sequence typing clades (clades C1 to C3), and clade C3 predominantly consists of isolates from the ... -
Stainless steel crown vs bulk fill composites for the restoration of primary molars post-pulpectomy: 1-year survival and acceptance results of a randomized clinical trial
(2022)Background: A key factor for the success and longevity of the endodontic treatment is sealing of the cavity after restorative treatment. Aim: The aim of this randomised clinical trial was to evaluate the 1-year survival ... -
A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.
(2008)Abstract: Lung cancer is the most common cause of cancer death worldwide, with over one million cases annually(1). To identify genetic factors that modify disease risk, we conducted a genome- wide association study by ... -
Tooth agenesis in patients referred to an Irish tertiary care clinic for the developmental dental disorders
(Irish Dental Association, 2010)PURPOSE: This study was carried out to determine the prevalence, severity and pattern of hypodontia in Irish patients referred to a tertiary care clinic for developmental dental disorders. MATERIALS AND METHODS: Details ... -
Transcript profiling reveals rewiring of iron assimilation gene expression in Candida albicans and C. dubliniensis
(2012)Hyphal growth is repressed in Candida albicans and C. dubliniensis by the transcription factor Nrg1. Transcript profiling of a C. dubliniensis NRG1 mutant identified a common group of 28 NRG1 repressed genes in both species, ... -
Triclosan antagonises fluconazole activity against Candida albicans
(2012)Triclosan is a broad-spectrum antimicrobial compound commonly used in oral hygiene products. Investigation of its activity against Candida albicans showed that triclosan was fungicidal at concentrations of 16 mg/L. However, ... -
Use of rubber dam versus cotton roll isolation on composite resin restorations' survival in primary molars: 2-year results from a non-inferiority clinical trial.
(2022)Background: This non-inferiority randomised clinical trial aimed to evaluate the survival of direct bulk fill composite resin restorations in primary molars using different methods of moisture control: rubber dam isolation ... -
Water fluoridation, dentition status and bone health of older people in Ireland
(2015)Objective To examine some of the potential benefits and risks of water fluoridation for older adults. Methods This study used ‘The Irish Longitudinal Study on Ageing’, to access a nationally representative sample ...