Browsing Histopathology & Morbid Anatomy (Scholarly Publications) by Subject "Resistance; Comparative; Selection strategy; Ovarian cancer; BRCA1; Carboplatin; Taxol"
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Carboplatin and taxol resistance develops more rapidly in functional BRCA1 compared to dysfunctional BRCA1 ovarian cancer cells
(2014)A major risk factor for ovarian cancer is germline mutations of BRCA1/2. It has been found that (80%) of cellular models with acquired platinum or taxane resistance display an inverse resistance relationship, that is ...