Browsing Biochemistry (Scholarly Publications) by Author "Yamamoto, Masayuki"
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5-aminolevulinic acid (ALA) deficiency causes impaired glucose tolerance and insulin resistance coincident with an attenuation of mitochondrial function in aged mice
KELLY, VINCENT; Saitoh, Shinichi; Okano, Satoshi; Nohara, Hidekazu; Nakano, Hiroshi; Shirasawa, Nobuyuki; Naito, Akira; Yamamoto, Masayuki; Kelly, Vincent P.; Takahashi, Kiwamu; Tanaka, Tohru; Nakajima, Motowo; Nakajima, Osamu (2018)In vertebrates, the initial step in heme biosynthesis is the production of 5-aminolevulinic acid (ALA) by ALA synthase (ALAS). ALA formation is believed to be the rate-limiting step for cellular heme production. Recently, ...