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  • Malonylation of GAPDH is an inflammatory signal in macrophages 

    O'Neill, Luke; Galván-Peña, Silvia; Carroll, Richard G.; Newman, Carla; Hinchy, Elizabeth C.; Palsson-McDermott, Eva; Robinson, Elektra K.; Covarrubias, Sergio; Nadin, Alan; James, Andrew M.; Haneklaus, Moritz; Carpenter, Susan; Kelly, Vincent P.; Murphy, Michael P.; Modis, Louise K. (2019)
    Macrophages undergo metabolic changes during activation that are coupled to functional responses. The gram negative bacterial product lipopolysaccharide (LPS) is especially potent at driving metabolic reprogramming, enhancing ...