Paediatrics (Theses and Dissertations)
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CRADLE - Circadian Rhythm Alteration anD neonataL Encephalopathy
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2023)Background: Neonatal Encephalopathy (NE) is a clinically defined syndrome of disturbed neurological function in the earliest days of life in term and near-term newborns. NE remains a major cause of mortality and morbidity ... -
SERENITY: SEveRE Neurological Impairment and children with medical complexiTY
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2022)Background and aims Children with Severe Neurological Impairment (SNI) have a significant disability as a result of a global impairment of the nervous system. They may be considered to be a subgroup of children with more ... -
Gender and Neonatal Inflammation in Preterm Outcome
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2021)Introduction: Preterm neonates are at high risk of sepsis and sepsis-related complications. Despite the prominence of sepsis in neonatal practice, there is no consensus definition and the role of organ dysfunction in ... -
PAEDIATRIC OUTCOMES AND SERUM BIOMARKER PANEL IN ACUTE TRAUMATIC BRAIN INJURY /CONCUSSION TO SEVERE TRAUMATIC BRAIN INJURY
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2020)Introduction Paediatric mild traumatic brain injury (mTBI) is increasingly recognised to have significant longer term neurocognitive effects. Childhood is a time of high risk for head injury. There were no national ... -
UNICORN; Underlying mechanisms in Neonatal Immune Metabolic Dysregulation and Brain Injury
(Trinity College Dublin. School of Medicine. Discipline of Paediatrics, 2020)Introduction: Neonatal encephalopathy (NE) is a clinically defined syndrome of disturbed neurologic function, in the earliest days of life. NE has a multifactorial aetiology and causes significant mortality and neurological ...