Browsing by Author "Wolfe, Amber M."

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  • Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. 

    Budanov, Andrei; Lee, Jun Hee; Talukdar, Saswata; Park, Eek Joong; Park, Hae Li; Park, Hwan-Woo; Bandyopadhyay, Gautam; Li, Ning; Aghajan, Mariam; Jang, Insook; Wolfe, Amber M.; Perkins, Guy A.; Ellisman, Mark H.; Bier, Ethan; Scadeng, Miriam; Foretz, Marc; Viollet, Benoit; Olefsky, Jerrold; Karin, Michael (2012)
    Chronic activation of mammalian target of rapamycin complex 1 (mTORC1) and p70 S6 kinase (S6K) in response to hypernutrition contributes to obesity-associated metabolic pathologies, including hepatosteatosis and insulin ...