Browsing by Subject "T-cell migration - PBOX - Tubulin"
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A new microtubule-targeting compound PBOX-15 inhibits T-cell migration via post-translational modifications of tubulin. (Springer, 2008)The ordered, directional migration of T-lymphocytes is a key process during immune surveillance, immune response, and development. A novel series of pyrrolo-1,5-benzoxazepines have been shown to potently induce apoptosis ...