Browsing by Author "Nakagome, Shigeki"
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Comment on "Nuclear genomic sequences reveal that polar bears are an old and distinct bear lineage".
Nakagome, Shigeki; Mano, Shuhei; Hasegawa, Masami (2013)Based on nuclear and mitochondrial DNA, Hailer et al. (Reports, 20 April 2012, p. 344) suggested early divergence of polar bears from a common ancestor with brown bears and subsequent introgression. Our population genetic ... -
Inferring the model and onset of natural selection under varying population size from the site frequency spectrum and haplotype structure
Nakagome, Shigeki; Hudson, Richard R.; Di Rienzo, Anna (2019)A fundamental question about adaptation in a population is the time of onset of the selective pressure acting on beneficial alleles. Inferring this time, in turn, depends on the selection model. We develop a framework of ... -
A time transect of exomes from a Native American population before and after European contact
Nakagome, Shigeki (2016)A major factor for the population decline of Native Americans after European contact has been attributed to infectious disease susceptibility. To investigate whether a pre-existing genetic component contributed to this ...