Browsing by Subject "tissue engineering"
Now showing items 1-7 of 7
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3D Bioprinting of Anatomically Accurate Implants for Meniscus Tissue Engineering
(Trinity College Dublin. School of Medicine. Discipline of Surgery, 2020)Menisci are soft tissues essential for load bearing and stress distribution in the knee joint. Meniscal injuries are common in all age groups and can lead to degeneration of the joint. While currently available surgical ... -
3D bioprinting of cartilage-mimetic implants for biological joint resurfacing
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)A major challenge in the field of tissue engineering and regenerative medicine is the development of effective therapies for treating large cartilage or osteochondral defects and ultimately regenerating whole osteoarthritic ... -
Development and characterization of corneal substitutes from decellularized tissues
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)Diseases affecting the cornea can lead to vision impairment and ultimately to blindness. It is estimated that 45 million people worldwide suffer from corneal blindness. Rejection in high-risk patients and donor shortage ... -
Development of mechanobiomimetic strategies to drive stem cell behaviour for bone regeneration
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)There are a host of cases where clinical intervention must be taken to treat diseased or damaged bone, including severe fractures, defects, tumours requiring tissue removal, and debilitating diseases such as osteoporosis. ... -
Effect of a degraded core on the mechanical behaviour of tissue-engineered cartilage constructs: a poro-elastic finite element analysis
(Springer, 2004)The structure and functionality of tissue-engineered cartilage is determined by the tissue culture conditions and mechanical conditioning during growth. The quality of tissue-engineered cartilage can be evaluated using ... -
The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering.
(IOS Press, 2007)The permeability of scaffolds and other three-dimensional constructs used for tissue engineering applications is important as it controls the diffusion of nutrients in and waste out of the scaffold as well as influencing ... -
Part 1: scaffolds and surfaces.
(Elsevier, 2008)Every day thousands of clinical procedures are performed to replace or repair tissues in the human body that have been damaged through disease or trauma. Current therapies are focused on the replacement of the damaged ...