Browsing by Subject "membrane proteins"
Now showing items 1-6 of 6
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Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination
(2014)Membrane proteins are key elements in cell physiology and drug targeting, but getting a high-resolution structure by crystallographic means is still enormously challenging. Novel strategies are in big demand to facilitate ... -
Crystallizing Transmembrane Peptides in Lipidic Mesophases
(2010)Structure determination of membrane proteins by crystallographic means has been facilitated by crystallization in lipidic mesophases. It has been suggested, however, that this so-called in meso method, as originally ... -
A fast, simple and robust protocol for growing crystals in the lipidic cubic phase
(2012)A simple and inexpensive protocol for producing crystals in the sticky and viscous mesophase used for membrane protein crystallization by the in meso method is described. It provides crystals that appear within 15–30 min ... -
Interactions of tryptophan, tryptophan peptides and tryptophan alkyl esters at curved membrane interfaces.
(American Chemical Society, 2006)Motivated by on-going efforts to understand the mechanism of membrane protein crystallogenesis and transport in the lipidic cubic phase, the nature of the interaction between tryptophan and the bilayer/aqueous interface ...