Browsing by Subject "YAP"
Now showing items 1-3 of 3
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The effect of pore size within fibrous scaffolds fabricated using melt electrowriting on human bone marrow stem cell osteogenesis.
(2019)Limitations associated with current bone grafting materials has necessitated the development of synthetic scaffolds that mimic the native tissue for bone repair. Scaffold parameters such as pore size, pore interconnectivity, ... -
Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation
(University of Edinburgh (datashare), 2020)Background: Normal skeletal development, in particular ossification, joint formation and shape features of condyles, depends on appropriate mechanical input from embryonic movement but it is unknown how such physical stimuli ... -
Unravelling the role of mechanical cues on the chondrogenic differentiation of stem cells
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2019)The inability of adult articular cartilage to regenerate has motivated the development of tissue engineering strategies to repair cartilage defects before they progress to osteoarthritis. Common cell based strategies ...