Browsing by Subject "X-ray crystallography"
Now showing items 1-8 of 8
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Crystal structure of the integral membrane diacylglycerol kinase
(2013)Diacylglycerol kinase catalyses the ATP-dependent phosphorylation of diacylglycerol to phosphatidic acid for use in shuttling water-soluble components to membrane-derived oligosaccharide and lipopolysaccharide in the cell ... -
Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase
(2013)A systematic study of the crystallization of an α-helical, integral membrane enzyme, diacylglycerol kinase, DgkA, using the lipidic cubic mesophase or in meso method is described. These trials have resulted in the production ... -
Investigating the Impact of Conformational Molecular Engineering on the Crystal Packing of Cavity Forming Porphyrins
(2019)Herein we report the synthesis of 5,10,15,20-tetraaryl-(X)-substituted- 2,3,7,8,12,13,17,18-octaethylporphyrins (OETArXPs) and a structural investigation of their solid-state properties via small molecule X-ray diffraction. ... -
The shape of porphyrins
(2021)Porphyrin molecules are a widely exploited biochemical moiety, with uses in medicinal chemistry, sensing and materials science. The shape of porphyrins, as an aromatic unit, is reductively imagined to be approximately flat, ... -
Solid-state supramolecular architectures of a series of Hg(II) halide coordination compounds based on hydroxyl-substituted Schiff base ligands
(2019)Crystal engineering of coordination complexes has become an important research domain of modern inorganic chemistry. Herein, six Hg(II) coordination compounds containing 2- ((pyridin-3-ylmethylene)amino)phenol and ... -
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
(2019)Microtubule-targeting agents (MTAs) are a class of clinically successful anti-cancer drugs. The emergence of multidrug resistance to MTAs imposes the need for developing new MTAs endowed with diverse mechanistic properties. ...