Browsing by Subject "SIGIRR"
Now showing items 1-2 of 2
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α-TLR2 antibody attenuates the Aβ-mediated inflammatory response in microglia through enhanced expression of SIGIRR.
(2015)The immunoregulatory function of single-Ig-interleukin-1 related receptor (SIGIRR) is derived from its ability to constrain the inflammatory consequences of interleukin (IL)-1R and toll-like receptor (TLR)4 activation. ... -
SIGIRR modulates the inflammatory response in the brain
(Elsevier, 2010)One of the more recently described members of the interleukin-1 (IL-1) receptor family, single-Ig-Interleukin-1 related receptor (SIGIRR), has been identified as a negative regulator of inflammation in several tissues. ...