Browsing by Subject "Plasmodium falciparum"
Now showing items 1-3 of 3
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Anti-malarial effects of macrolactones related to FK520 (ascomycin) are independent of the immunosuppressive properties of the compounds
(University of Chicago Press, 2005)The polyketide macrolactone FK506 inhibits the growth of Plasmodium falciparum in culture and the enzymatic (peptidyl-prolyl cis-trans isomerase [PPIase]) and chaperone activities of a recently identified P. falciparum ... -
Downstream Effects of Haemoglobinase Inhibition in Plasmodium falciparum-Infected Erythrocytes
(2010)Blood-stage malarial parasites (Plasmodium falciparum) digest large quantities of host haemoglobin during their asexual development in erythrocytes. The haemoglobin digestion pathway, involving a succession of cleavages ... -
Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration
(2021)Pathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the parasitic disease malaria caused by Plasmodium falciparum. ...