Browsing by Subject "Osteochondral"
Now showing items 1-4 of 4
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3D printing of fibre-reinforced cartilaginous templates for the regeneration of osteochondral defects
(2020)Successful osteochondral defect repair requires regenerating the subchondral bone whilst simultaneously promoting the development of an overlying layer of articular cartilage that is resistant to vascularization and ... -
Biofabrication of spatially organised tissues by directing the growth of cellular spheroids within 3D printed polymeric microchambers
(2019)Successful tissue engineering requires the generation of human scale implants that mimic the structure, composition and mechanical properties of native tissues. Here, we report a novel biofabrication strategy that enables ... -
BIOFABRICATION STRATEGIES TO GUIDE THE SELF-ORGANISATION OF BIOMIMETIC CARTILAGE AND OSTEOCHONDRAL TISSUES
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2021)The modest clinical impact of musculoskeletal tissue engineering (TE) can be attributed, at least in part, to a failure to recapitulate the structure, composition and functional properties of the target tissue. This has ... -
The development of biomimetic scaffolds for osteochondral tissue engineering
(Trinity College Dublin. School of Engineering. Discipline of Mechanical & Manuf. Eng, 2020)Articular cartilage (AC) is a soft tissue lining the ends of the bones in our joints. Even minor lesions in AC cause pain, impaired mobility and can develop to osteoarthritis (OA), a disease affecting millions of adults ...