Browsing by Subject "Liability"

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  • Extending the Construct Network of Trait Disinhibition to the Neuroimaging Domain: Validation of a Bridging Scale for Use in the European IMAGEN Project 

    Bokde, Arun; Whelan, Robert; Brislin, Sarah J.; Patrick, Christopher J.; Flor, Herta; Nees, Frauke; Heinrich, Angela; Drislane, Laura E.; Yancey, James R.; Banaschewski, Tobias; Bromberg, Uli; Büchel, Christian; Burke Quinlan, Erin; Desrivieres, Sylvane; Frouin, Vincent; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Ittermann, Bernd; Martinot, Jean-Luc; Paillère Martinot, Marie-Laure; Fröhner, Juliane H.; Smolka, Michael N.; Walter, Henrik; Conrod, Patricia; Stringaris, Argyris; Struve, Maren; van Noort, Betteke; Grimmer, Yvonne; Fadai, Tahmine; Schumann, Gunter; Foell, Jens; Papadopoulos Orfanos, Dimitri (2019)
    Trait disinhibition, a clinical-liability construct, has well-established correlates in the diagnostic, self-rating, task-behavioral, and brain potential response domains. Recently, studies have begun to test for neuroimaging ...

  • Large-Scale Exome Sequencing Study Implicates Both Developmental and Functional Changes in the Neurobiology of Autism 

    Gallagher, Louise (2020)
    We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n = 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to integrate de novo and case-control rare variation, ...