Browsing by Subject "Immune response"
Now showing items 1-14 of 14
-
Competition for nutrients; an emerging role in controlling immune responses
(2019)Changes in cellular metabolism are associated with the activation of diverse immune subsets. These changes are fuelled by nutrients including glucose, amino acids and fatty acids, and are closely linked to immune cell fate ... -
Evidence summary of the immune response following infection with SARS-CoV-2 or other human coronaviruses
(Health Information and Quality Authority, ireland, 2020-06-09) -
Evidence summary of the immune response following infection with SARS-CoV-2 or other human coronaviruses
(Health Information and Quality Authority, ireland, 2020-05-13) -
Evidence summary of the immune response following infection with SARS-CoV-2 or other human coronaviruses
(Health Information and Quality Authority, ireland, 2020-08-06) -
Glyoxal cross-linking of solubilized extracellular matrix to produce highly porous, elastic, and chondro-permissive scaffolds for orthopedic tissue engineering
(2019)Extracellular matrix (ECM)-derived implants hold great promise for tissue repair, but new strategies are required to produce efficiently decellularized scaffolds with the necessary porosity and mechanical properties to ... -
Halloysite- and Montmorillonite-Loaded Scaffolds as Enhancers of Chronic Wound Healing
(2020)The increase in life expectancy and the increasing prevalence of diabetic disease and venous insufficiency lead to the increase of chronic wounds. The prevalence of ulcers ranges from 1% in the adult population to 3–5% in ... -
Immunometabolism and Natural Killer cell responses
(2019)Natural killer (NK) cells are lymphocytes with important roles in innate and adaptive immune responses to tumours and viral infection. However, in certain chronic diseases, including obesity and cancer, NK cell functional ... -
Macrophages in the cochlea; an immunological link between risk factors and progressive hearing loss
(2022)Macrophages are abundant in the cochlea; however, their role in hearing loss is not well understood. Insults to the cochlea, such as noise or insertion of a cochlear implant, cause an inflammatory response, which includes ... -
Nano-particle mediated M2 macrophage polarization enhances bone formation and MSC osteogenesis in an IL-10 dependent manner
(2020)Engineering a pro-regenerative immune response following scaffold implantation is integral to functional tissue regeneration. The immune response to implanted biomaterials is determined by multiple factors, including ... -
A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata exhibits outstanding anti-tumor activity in melanoma.
(2014)Hemocyanins, the huge oxygen-transporting glycoproteins of some mollusks, are used as immunomodulatory proteins with proven anti-cancer properties. The biodiversity of hemocyanins has promoted interest in identifying new ... -
A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.
(2011)Clostridium difficile is the etiological agent of antibiotic-associated diarrhoea (AAD) and pseudomembranous colitis in humans. The role of the surface layer proteins (SLPs) in this disease has not yet been fully explored. ... -
The role of lymphocytes in neonatal encephalopathy.
(2021)Neonatal encephalopathy is a syndrome characterised by abnormal neurological function often caused by a hypoxic insult during childbirth. Triggers such as hypoxia-ischaemia result in the release of cytokines and chemokines ... -
Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro
(BioMed Central Ltd, 2013)Background Mycobacterium bovis, the causative agent of bovine tuberculosis, is an intracellular pathogen that can persist inside host macrophages during infection via a diverse range of mechanisms that subvert the host ...