Browsing by Subject "IL-27"
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IL-27 mediates the response to IFN beta therapy in multiple sclerosis patients by inhibiting Th17 cells
(2011)Interferon (IFN)-? is a commonly used therapy for relapsing remitting multiple sclerosis (RRMS). However its protective mechanism is still unclear and the failure of many patients to respond has not been explained. We have ... -
Investigation of Staphylococcus aureus-induced immunosuppression during nasal colonisation and the implications for vaccine function
(Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2023)Staphylococcus aureus (S. aureus) is a major part of the natural human microbiome, primarily colonising the anterior nares. The overall aim of this project was to determine the impacts nasal colonisation has on local and ...