Browsing by Subject "Genome"

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  • Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation 

    Whelan, Robert; Bokde, Arun; Hongtao, Ruan; Zhou, Yunyi; Qiang, Luo; Robert, Gabriel H.; Desrivieres, Sylvane; Burke Quinlan, Erin; Liu, ZhaoWen; Banaschewski, Tobias; Bromberg, Uli; Büchel, Christian; Flor, Herta; Frouin, Vincent; Garavan, Hugh; Gowland, Penny; Heinz, Andreas; Itterman, Bernd; Martinot, Jean-Luc; Paillère Martinot, Marie-Laure; Nees, Frauke; Papadopoulos Orfanos, Dimitri; Poustka, Luise; Hohmann, Sarah; Fröhner, Juliane H.; Smolka, Michael N.; Walter, Henrik; Li, Fei; Schumann, Gunter; Feng, Jianfeng (2019)
    Adolescent binge drinking has been associated with higher risks for the development of many health problems throughout the lifespan. Adolescents undergo multiple changes that involve the co-development processes of brain, ...

  • Decisions, Decisions: Machine Learning as a Tool to Identify Alcohol-use Disorder Treatment Seekers 

    Whelan, Robert (Elsevier, 2019)
    Alcohol use disorders (AUD) are very common in the developed world [1], yet only a minority of individuals with AUD seek treatment. Several factors influence the choice to seek treatment, including demographic, psychological ...

  • Genotypic and phenotypic insights into an Irish axial spondyloarthritis cohort 

    Kenyon, Marcus (Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)
    Axial spondyloarthritis (AxSpA) encompasses a group of closely related chronic inflammatory conditions which primarily affect the lumbar spine. The prototypic presentation of the disease is ankylosing spondylitis, which ...

  • Herding Ancient Domesticates: From Bones to Genomes 

    MULLIN, VICTORIA ELIZABETH (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)
    This thesis demonstrates the power of the analysis of ancient domesticate genomes of cattle and sheep in order to analyse past population dynamics of the two species. In total 113 whole genomes and 127 mitogenomes of wild ...