Browsing by Subject "Dementia"
Now showing items 1-20 of 45
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Acute hospital staff s attitudes towards dementia and perceived dementia knowledge: a cross-sectional survey in Ireland
(2020)Background: Little is known about staff’s attitudes in Irish acute hospital settings towards people living with dementia and their perceived dementia knowledge. The aim of this study was to understand the general level of ... -
Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium
(2020)Systemic infection triggers a spectrum of metabolic and behavioral changes, collectively termed sickness behavior, which while adaptive, can affect mood and cognition. In vulnerable individuals, acute illness can also ... -
Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1?? drives amplified responses in primed astrocytes and neuronal network dysfunction
(2021)Neuroinflammation contributes to Alzheimer’s disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require ... -
Age-related hearing loss and neurocognitive function: Normal and pathological processes in cognitive ageing
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2018)This thesis investigates age-related hearing loss (ARHL) as a potential biomarker and risk factor for cognitive decline and dementia. Two reviews were conducted to examine the evidence for an association in the epidemiological ... -
At home activities: A selection of meaningful activities for people with dementia, families and carers
(Health Service ExecutiveIE, 2020-04-23) -
Building Consensus for the Future : Report of the Feasibility Study on Palliative Care for People with Dementia
(Irish Hospice FoundationIE, 2012-12) -
Cognitive impairment before and after intracerebral haemorrhage: a systematic review.
(2020)Introduction: There is increasing interest in understanding cognitive dysfunction before and after Intracerebral haemorrhage (ICH), given the higher prevalence of dementia reported (ranging from 5 to 44%) for this stroke ... -
Cognitive reserve and dementia risk management in people with an intellectual disability.
(2023)Dementia risk is elevated in people with intellectual disability, particularly for those with Down syndrome Differences in lifestyle factors have been cited as factors that exacerbate dementia risk in people with ... -
A collection of online resources for people with dementia, families and carers
(Health Service Executive [and five others]IE, 2020-04-09) -
Creating Excellence in Dementia Care
(2012)The estimated cost of formal and informal care for dementia worldwide is currently in excess of 600 billion dollars accounting for 1% of the world?s gross domestic product. This cost, which will grow substantially in the ... -
Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study.
(2012)Recent studies suggest that delirium is associated with risk of dementia and also acceleration of decline in existing dementia. However, previous studies may have been confounded by incomplete ascertainment of cognitive ... -
Dementia - a geriatric syndrome
(2013) -
Dementia in the Acute General Hospital - Prevalence, Practices and Outcomes
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2019)Background The number of people living with dementia in Ireland is projected to increase exponentially in the coming decades. The international literature suggests, however, that the recognition of dementia is poor, ... -
Detection of prospective memory deficits in mild cognitive impairment of suspected Alzheimer's disease etiology using a novel event-based prospective memory task.
(2009)We investigated the relative discriminatory efficacy of an event-based prospective memory (PM) task, in which specificity of the instructions and perceptual salience of the PM cue were manipulated, compared with two widely ... -
Diabetes and Brain Health
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2020)Introduction: Type 2 diabetes mellitus (T2DM), one of the most common non-communicable diseases in the world, is linked to multi-organ complications. Such complications include cognitive impairment, dementia and depression. ... -
Driving assessment for maintaining mobility and safety in drivers with dementia.
(2013)Abstract Background Demographic changes are leading to an increase in the number of older drivers: as dementia is an age-related disease, there is also an increase in the numbers of drivers with dementia. Dementia can ... -
Examining the effects of cognitive training on levels of executive function in adults with down syndrome: A feasibility study
(Trinity College Dublin. School of Nursing & Midwifery. Discipline of Nursing, 2017)Introduction Individuals with Down syndrome are at much greater risk of developing AD, and one of the early clinical symptoms of AD is executive dysfunction. In the general population, cognitive training has shown some ... -
Extracellular forms of A� and tau from iPSC models of Alzheimer's disease disrupt synaptic plasticity
(2018)The early stages of Alzheimer’s disease are associated with synaptic dysfunction prior to overt loss of neurons. To identify extracellular molecules that impair synaptic plasticity in the brain, we studied the secretomes ... -
Guidance Document 1: Facilitating discussions on future and end-of-life care with a person with dementia
(Irish Hospice FoundationIE, 2015) -
Guidance Document 2: Advance care planning and advance healthcare directives with a person with dementia
(Irish Hospice FoundationIE, 2016)