Browsing by Subject "DNA Repair"
Now showing items 1-3 of 3
ERCC1 expression and RAD51B activity correlate with cell cycle response to platinum drug treatment not DNA repair. (Springer Verlag, 2009)Background: The H69CIS200 and H69OX400 cell lines are novel models of low- level platinum-drug resistance. Resistance was not associated with increased cellular glutathione or decreased accumulation of platinum, rather ...
(2011)Searching for a novel family of inactivators of the human DNA repair protein O6?methylguanine?DNA methyltransferase (MGMT) which is known to bind to the DNA minor groove, we have computationally modelled and synthesised ...