Browsing by Subject "Chemotherapy"
Now showing items 1-13 of 13
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Biocompatible copolymer formulations to treat glioblastoma multiforme.
(2021)The treatment for glioblastoma multiforme (GBM) has not changed for more than 20 years while the prognosis for the patients is still poor and most of them survive less than 1 year after diagnosis. The standard of care for ... -
CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies
(2020)Esophageal and gastric cancers collectively cause over 1.1 million deaths annually and only 20-30% of patients respond favorably to current therapies. Cellular therapies using invariant natural killer T (iNKT) cells are ... -
Cooperation between chemotherapy and immunotherapy in gastroesophageal cancers
(2020)Gastroesophageal cancers (GOCs) represent some of the most common cancers globally and are linked with poor survival rates. The current standard of care includes multimodal chemotherapy, radiotherapy and surgery. However, ... -
Efficacy of resistance training during adjuvant chemotherapy and radiation therapy in cancer care: a systematic review and meta-analysis
(2022)Purpose: To determine the effect of resistance training during adjuvant chemotherapy and radiation therapy in cancer patients on measures of lean mass and muscle strength. Secondary aims were to analyse the prescription ... -
Metastatic disease in head & neck oncology
(2020)The head and neck district represents one of the most frequent sites of cancer, and the percentage of metastases is very high in both loco-regional and distant areas. Prognosis refers to several factors: a) stage of disease; ... -
NCCP patient pathway for attendance for SACT on a haematology/oncology day ward during the COVID- 19 pandemic
(Health Service ExecutiveIE, 2020-06-18) -
Optimised oligonucleotide substrates to assay XPF-ERCC1 nuclease activity for the discovery of DNA repair inhibitors
(2019)We report the design and optimisation of novel oligonucleotide substrates for a sensitive fluorescence assay for high-throughput screening and functional studies of the DNA repair enzyme, XPFERCC1, with a view to ... -
Understanding chemotherapy
(Irish Cancer SocietyIE, 2012) -
Understanding Chemotherapy : Caring for people with cancer
(Irish Cancer SocietyIE, 2015) -
Understanding cisplatin resistance using cellular models.
(John Wiley, 2007)Many mechanisms of cisplatin resistance have been proposed from studies of cellular models of resistance including changes in cellular drug accumulation, detoxification of the drug, inhibition of apoptosis and repair of ...