Browsing by Subject "CCL2"
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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1?? drives amplified responses in primed astrocytes and neuronal network dysfunction
(2021)Neuroinflammation contributes to Alzheimer’s disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require ... -
A Systematic Analysis of the Peripheral and CNS Effects of Systemic LPS, IL-1beta, TNF-alpha and IL-6 Challenges in C57BL/6 Mice.
(2013)It is increasingly clear that systemic inflammation has both adaptive and deleterious effects on the brain. However, detailed comparisons of brain effects of systemic challenges with different pro-inflammatory cytokines ...