Browsing by Subject "CANCER"
Now showing items 1-20 of 31
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Aspirin and P2Y<inf>12</inf> inhibition attenuate platelet-induced ovarian cancer cell invasion
(2015)Background: Platelet-cancer cell interactions play a key role in successful haematogenous metastasis. Disseminated malignancy is the leading cause of death among ovarian cancer patients. It is unknown why different ovarian ... -
Comparing the Effects of Intracellular and Extracellular Magnetic Hyperthermia on the Viability of BxPC-3 Cells
(2020)Magnetic hyperthermia involves the use of iron oxide nanoparticles to generate heat in tumours following stimulation with alternating magnetic fields. In recent times, this treatment has undergone numerous clinical trials ... -
Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.
(2013)Weighted gene coexpression network analysis (WGCNA) is a powerful 'guilt-by-association'-based method to extract coexpressed groups of genes from large heterogeneous messenger RNA expression data sets. We have utilized ... -
The cost of survival: an exploration of colorectal cancer survivors? experiences of pain
(2017)Background: The Institute of Medicine report ‘From Cancer Patient to Cancer Survivor’ has drawn widespread attention to the experiences of cancer survivors. Research examining the symptom experiences of survivors are ... -
Evaluation of the effect of solid and cationic lipids on siRNA delivery systems
(2020)This study aims to develop nanoparticles with different types of solid and cationic lipids and evaluate them as siRNA delivery systems. For this purpose, we prepared a series of lipid nanoparticles by combining cationic ... -
Evidence for the Need to Evaluate More Than One Source of Extracellular Vesicles, Rather Than Single or Pooled Samples Only, When Comparing Extracellular Vesicles Separation Methods
(2021)To study and exploit extracellular vesicles (EVs) for clinical benefit as biomarkers, therapeutics, or drug delivery vehicles in diseases such as cancer, typically we need to separate them from the biofluid into which they ... -
Extracellular vesicles in blood: are they viable as diagnostic and predictive tools in breast cancer?
(2020)Extracellular vesicles (EVs), often described as mini-maps of their cells of origin, are found in the bloodstream and can be rich sources of cargo released from cancer cells. As such, they could be collected through minimally ... -
Factors influencing adherence to a calorie posting policy in Irish public hospitals. SPHeRE Policy Brief
(SPHeRE, 2022)Evidence shows calorie posting has positive effects on consumer food choice and industry/catering practices; however, few studies report the extent to which calorie posting is implemented as designed. The current study ... -
The future of Extracellular Vesicles as Theranostics - an ISEV meeting report
(2020)The utilization of extracellular vesicles (EVs) in clinical theranostics has rapidly advanced in the past decade. In November 2018, the International Society for Extracellular Vesicles (ISEV) held a workshop on “EVs in ... -
Gene Expression Profiling
(Humana Press, 2009) -
Identifying Associations Between Quality of Life Outcomes and Healthcare-Related Variables Among Colorectal Cancer Survivors: A Cross-Sectional Survey Study
(2019)Background: Follow-up care and surveillance are essential components of colorectal cancer survivorship. However, the relative contribution of healthcare experiences to quality of life in cancer survivorship is poorly ... -
Inhibiting extracellular vesicles formation and release: a review of EV inhibitors.
(2019)It is now becoming well established that vesicles are released from a broad range of cell types and are involved in cell-to-cell communication, both in physiological and pathological conditions. Once outside the cell, these ... -
ISEV position paper: extracellular vesicle RNA analysis and bioinformatics.
(2013)Extracellular vesicles (EVs) are the collective term for the various vesicles that are released by cells into the extracellular space. Such vesicles include exosomes and microvesicles, which vary by their size and/or protein ... -
A method of separating extracellular vesicles from blood shows potential clinical translation, and reveals extracellular vesicle cargo gremlin-1 as a diagnostic biomarker
(2022)Extracellular vesicles (EVs) have potential as minimally invasive biomarkers. However, the methods most commonly used for EV retrieval rely on ultracentrifugation, are time-consuming, and unrealistic to translate to ... -
MicroRNA Profiling of Exosomes
(Springer, 2017)