Browsing by Subject "Breast cancer"
Now showing items 1-20 of 25
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Benzoxepin-Type Selective Estrogen Receptor (ER) Modulators and Downregulators with Subtype-Specific ERα and ERβ Activity
(2018)The two nuclear estrogen receptors (ERα and ERβ) mediate the biological effects of the estrogen hormones and ERα is an attractive therapeutic target for diseases including breast cancer and osteoporosis. Estrogens are known ... -
Breast Cancer : What you should know
(Irish Cancer Society, ireland, 2017) -
Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.
(2013)Weighted gene coexpression network analysis (WGCNA) is a powerful 'guilt-by-association'-based method to extract coexpressed groups of genes from large heterogeneous messenger RNA expression data sets. We have utilized ... -
Ductal carcinoma in situ (DCIS)
(Irish Cancer Society, ireland, 2013) -
Ductal carcinoma in situ (DCIS)
(Irish Cancer Society, ireland, 2011) -
Exosomes from triple-negative breast cancer cells can transfer phenotypic traits representing their cells of origin to secondary cells
(2013)Background Triple-negative breast cancer (TNBC) accounts for 15–20% of breast cancers but is responsible for a disproportionate number of deaths. We investigated the relevance, in TNBC, of nano-sized exosomes expelled ... -
Investigating mechanisms of anti-cancer drug resistance in breast cancer cells and extracellular vesicles
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2019)Breast cancer is the most common female cancer diagnosed worldwide. In 2018 alone, there were over 2 million new breast cancer cases diagnosed. In Ireland, breast cancer is the most commonly diagnosed cancer in women. In ... -
An investigation into the provision, fitting and supply of external breast prostheses: a national study
(Irish Cancer Society, ireland, 2006-11) -
The presentation of metabolic dysfunction and the relationship with energy output in breast cancer survivors: a cross-sectional study.
(2013)Background Breast cancer prognosis can be adversely influenced by obesity, physical inactivity and metabolic dysfunction. Interventions aimed at improving surrogate markers of breast cancer risk such as insulin resistance ... -
A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers
(2013)Background Breast cancer is the most common female cancer worldwide. The lifetime risk of a woman being diagnosed with breast cancer is approximately 12.5%. For women who carry the deleterious mutation in either of the ... -
A prospective investigation of predictive and modifiable risk factors for breast cancer in unaffected BRCA1 and BRCA2 gene carriers
(2013)Background Breast cancer is the most common female cancer worldwide. The lifetime risk of a woman being diagnosed with breast cancer is approximately 12.5%. For women who carry the deleterious mutation in either of the ... -
Radiotherapy and breast cancer
(Irish Cancer Society, ireland, 2014) -
Sexuality and breast cancer
(Irish Cancer Society, ireland, 2013) -
Standards of care for breast prosthesis fitting services
(Irish Cancer Society, ireland, 2006) -
The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers.
(2009)The TP53 pathway, in which TP53 and its negative regulator MDM2 are the central elements, has an important role in carcinogenesis, particularly in BRCA1- and BRCA2-mediated carcinogenesis. A single nucleotide polymorphism ... -
Understanding breast reconstruction
(Irish Cancer Society, ireland, 2013)
