Browsing by Subject "Alzheimer’s disease (AD)"
Now showing items 1-4 of 4
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Acute systemic inflammation exacerbates neuroinflammation in Alzheimer's disease: IL-1?? drives amplified responses in primed astrocytes and neuronal network dysfunction
(2021)Neuroinflammation contributes to Alzheimer’s disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require ... -
Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research
(2015)Dementia prevalence increases with age and Alzheimer’s disease (AD) accounts for up to 75% of cases. However, significant variability and overlap exists in the extent of amyloid-β and Tau pathology in AD and non-demented ... -
Cognitive rehabilitation for early stage Alzheimer's disease: a pilot study with an Irish population
(2019)Objectives: Research shows that cognitive rehabilitation (CR) has the potential to improve goal performance and enhance well-being for people with early stage Alzheimer’s disease (AD). This single subject, multiple baseline ... -
Measuring network disruption in neurodegenerative diseases: New approaches using signal analysis.
(2019)Advanced neuroimaging has increased understanding of the pathogenesis and spread of disease, and offered new therapeutic targets. MRI and positron emission tomography have shown that neurodegenerative diseases including ...