Browsing by Author "Vajda, Alice"
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Genetic testing in ALS: A survey of current practices
MCLAUGHLIN, RUSSELL; HARDIMAN, ORLA; Vajda, Alice; Heverin, Mark; Thorpe, Owen; Abrahams, Sharon; Al-Chalabi, Ammar (2017)Objective: To determine the degree of consensus among clinicians on the clinical use of genetic testing in amyotrophic lateral sclerosis (ALS) and the factors that determine decision-making. Methods: ALS researchers ... -
In vitro modelling of androgen-mediated gene-directed enzyme prodrug therapy for the treatment of prostate cancer
Vajda, Alice (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Radiation Therapy, 2012)Gene-directed enzyme prodrug therapy has the potential to improve prostate cancer therapy outcome and could be used on its own or as an adjuvant to the current treatments. This research involved the characterisation of a ... -
What does the ALSFRS-R really measure? A longitudinal and survival analysis of functional dimension subscores in amyotrophic lateral sclerosis
Hardiman, Orla; Rooney, James; Burke, Tom; Vajda, Alice; Heverin, Mark (2017)Introduction: ALSFRS-R is the most widely used functional rating system in ALS patients. However, heterogeneity in ALSFRS-R progression renders analysis challenging. We have explored the characteristics of total ALSFRS-R, ...