Browsing by Author "Roberts, Kim"
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Contact transmission of influenza virus between ferrets imposes a looser bottleneck than respiratory droplet transmission allowing propagation of antiviral resistance
Roberts, Kim (2016)Influenza viruses cause annual seasonal epidemics and occasional pandemics. It is important to elucidate the stringency of bottlenecks during transmission to shed light on mechanisms that underlie the evolution and propagation ... -
Exploring the Applicability of Robot-Assisted UV Disinfection in Radiology
Mc Ginn, Conor; Roberts, Kim (2021)The importance of infection control procedures in hospital radiology departments has become increasingly apparent in recent months as the impact of COVID-19 has spread across the world. Existing disinfectant procedures ... -
Ferret airway epithelial cell cultures support efficient replication of influenza B virus but not mumps virus.
Roberts, Kim (2015)Ferrets have become the model animal of choice for influenza pathology and transmission experiments as they are permissive and susceptible to human influenza A viruses. However, inoculation of ferrets with mumps virus (MuV) ... -
Glycomic characterization of respiratory tract tissues of ferrets: Implications for its use in influenza virus infection studies
Roberts, Kim (2014)The initial recognition between influenza virus and the host cell is mediated by interactions between the viral surface protein hemagglutinin and sialic acid-terminated glycoconjugates on the host cell surface. The sialic ... -
A novel anti-viral role for STAT3 in IFN-α signalling responses.
Stevenson, Nigel; Bowie, Andrew; Roberts, Kim; Bourke, Nollaig; O'Farrelly, Cliona (Springer, 2017-05)The cytokine, Interferon (IFN)-α, induces a wide spectrum of anti-viral mediators, via the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway. STAT1 and STAT2 are well characterised ...