Browsing by Author "REYNOLDS, JOHN"
Now showing items 1-20 of 38
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A Barrett's esophagus registry of over 1000 patients from a specialist center highlights greater risk of progression than population-based registries and high risk of low grade dysplasia.
REYNOLDS, JOHN; O'SULLIVAN, JACINTHA; RAVI, NARAYANASAMY (2015) -
The characterization of an intestine-like genomic signature maintained during Barrett's-associated adenocarcinogenesis reveals an NR5A2-mediated promotion of cancer cell survival
SENGE, MATHIAS; REYNOLDS, JOHN (2016)Barrett’s oesophagus (BO), an intestinal-type metaplasia (IM), typically arising in conjunction with gastro-oesophageal reflux disease, is a prominent risk factor for the development of oesophageal adenocarcinoma (OAC). ... -
Common data items in seven European oesophagogastric cancer surgery registries: Towards a European Upper GI Cancer Audit (EURECCA Upper GI)
REYNOLDS, JOHN (2014)Aims Seven countries (Denmark, France, Ireland, the Netherlands, Poland, Sweden, United Kingdom) collaborated to initiate a EURECCA (European Registration of Cancer Care) Upper GI project. The aim of this study was to ... -
COX-Derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention
REYNOLDS, JOHN; O'SULLIVAN, JACINTHA; CATHCART, MARY CLARE; PIDGEON, GRAHAM; O'BYRNE, KEN (Elsevier, 2012)Arachidonic acid metabolism through cyclooxygenase (COX) pathways leads to the generation of biologically active eicosanoids. Eicosanoid expression levels vary during development and progression of gastrointestinal (GI) ... -
Defining a successful esophagectomy.
REYNOLDS, JOHN (2014) -
Deoxycholic acid promotes development of gastroesophageal reflux disease and Barrett's oesophagus by modulating integrin-??v trafficking
FINN, STEPHEN; O'SULLIVAN, JACINTHA; LONG, AIDEEN; BYRNE, ANNE-MARIE; REYNOLDS, JOHN (2017) -
Differential expression of mitochondrial energy metabolism profiles across the metaplasia-dysplasia-adenocarcinoma disease sequence in Barrett's oesophagus.
RAVI, NARAYANASAMY; O'SULLIVAN, JACINTHA; REYNOLDS, JOHN; LYNAM-LENNON, NIAMH (2014) -
Diffuse oesophageal leiomyomatosis.
FINN, STEPHEN; REYNOLDS, JOHN; MULDOON, CIAN; RAVI, NARAYANASAMY (2013) -
Dissecting intramural hematoma of the esophagus.
REYNOLDS, JOHN (2013) -
Elevated Tumor Expression of PAI-1 and SNAI2 in Obese Esophageal Adenocarcinoma Patients and Impact on Prognosis.
LYSAGHT, JOANNE; REYNOLDS, JOHN; PIDGEON, GRAHAM (2012) -
The esophagitis to adenocarcinoma sequence; the role of inflammation.
REYNOLDS, JOHN (2014) -
Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion
BYRNE, ANNE-MARIE; FINN, STEPHEN; REYNOLDS, JOHN; LONG, AIDEEN (2015)Background: The aetiology of Barrett’s oesophagus (BO) and oesophageal cancer is poorly understood. We previously demonstrated that Golgi structure and function is altered in oesophageal cancer cells. A Golgi-associated ... -
HLA-DR expression in tumor epithelium is an independent prognostic indicator in esophageal adenocarcinoma patients
Dunne, Margaret; REYNOLDS, JOHN; RAVI, NARAYANASAMY (2017) -
ICORG 10-14: NEOadjuvant trial in Adenocarcinoma of the oEsophagus and oesophagoGastric junction International Study (Neo-AEGIS)
REYNOLDS, JOHN; RAVI, NARAYANASAMY (2017) -
Images in clinical medicine. Intermittent facial flushing and diarrhea.
REYNOLDS, JOHN (2014) -
Internal hernia following total gastrectomy with Roux-en-Y reconstruction.
REYNOLDS, JOHN; RAVI, NARAYANASAMY (2011)Internal herniation is a well-described complication after a gastric bypass, particularly when performed laparoscopically, although it is rarely described following a total gastrectomy. A 55-year-old lady presented with ... -
LC3B globular structures correlate with survival in esophageal adenocarcinoma
O'SULLIVAN, JACINTHA; REYNOLDS, JOHN (2015)Background Esophageal adenocarcinoma has the fastest growing incidence of any solid tumor in the Western world. Prognosis remains poor with overall five-year survival rates under 25 %. Only a limited number of patients ... -
Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery.
PIDGEON, GRAHAM; REYNOLDS, JOHN; MAHER, STEPHEN; WHITE, BARRY; O'DONNELL, JAMES (2010)Background: The association between cancer, major surgery and venous thromboembolism (VTE) is well established. Multimodal therapy is increasingly being used as standard treatment for localised gastrointestinal ...