Browsing by Author "PRINA MELLO, ADRIELE"
Now showing items 1-20 of 20
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Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity
DAVIES, ANTHONY; VOLKOV, YURI; WILLIAMS, YVONNE; PRINA MELLO, ADRIELE; KELLEHER, DERMOT P (2011)Background: Nanomaterials such as SiO2 nanoparticles (SiO2NP) are finding increasing applications in the biomedical and biotechnological fields such as disease diagnostics, imaging, drug delivery, food, cosmetics and ... -
CdTe quantum dots induce activation of human platelets: Implications for nanoparticle hemocompatibility
PRINA MELLO, ADRIELE; SANTOS-MARTINEZ, MARIA; MEDINA MARTIN, CARLOS; VOLKOV, YURI (2015) -
Citrullination as early-stage indicator of cell response to single-walled carbon nanotubes.
PRINA MELLO, ADRIELE (2013)Single-walled carbon nanotubes (SWCNTs) have been widely explored as potential technologies for information systems and medical applications. The impact of SWCNTs on human health is of prime concern, if SWCNTs have a ... -
Detection of ErbB2: Nanotechnological solutions for clinical diagnostics
RAKOVICH, TATSIANA; PRINA MELLO, ADRIELE; MOVIA, DANIA; VOLKOV, YURI (2014) -
Determination of spiropyran cytotoxicity by high content screening and analysis for safe application in bionanosensing
GIORDANI, SILVIA; MOVIA, DANIA; VOLKOV, YURI; PRINA MELLO, ADRIELE (2010)The in vitro toxic response of spiropyrans in cellular models has not been previously addressed, despite the fact that such photoswitchable molecules have shown great potential as versatile and tunable components for ... -
Development of artificial neuronal networks for molecular communication
PRINA MELLO, ADRIELE; DELLA CHIESA, ANDREA; BOYLE, NOREEN (2011)Communication at the nanoscale can enhance capabilities for nanodevices, and at the same time open new opportunities for numerous healthcare applications. One approach towards enabling communication between nanodevices is ... -
Differential stress reaction of human colon cells to oleic-acid-stabilized and unstabilized ultrasmall iron oxide nanoparticles
MOVIA, DANIA; PRINA MELLO, ADRIELE (2014)Therapeutic engineered nanoparticles (NPs), including ultrasmall superparamagnetic iron oxide (USPIO) NPs, may accumulate in the lower digestive tract following ingestion or injection. In order to evaluate the reaction of ... -
Internalization of ferromagnetic nanowires by different living cells
PRINA MELLO, ADRIELE; COEY, JOHN (2006)The ability of living cells, either adherent or suspended, to internalize nickel nanowires is demonstrated for MC3T3-E1, UMR106-tumour and Marrow-Stromal cells. Nanowires were produced by electrodeposition, 20 mum long and ... -
Many particle magnetic dipole-dipole and hydrodynamic interactions in magnetizable stent assisted magnetic drug targeting
PRINA MELLO, ADRIELE (2010)The implant assisted magnetic targeted drug delivery system of Avil?es, Ebner and Ritter is considered both experimentally (in vitro) and theoretically. The results of a 2D mathematical model are compared with 3D experimental ... -
Multifactorial determinants that govern nanoparticle uptake by human endothelial cells under flow.
GOUNKO, IOURI; PRINA MELLO, ADRIELE; VOLKOV, YURI (2012) -
Nanotechnologies for the study of the central nervous system
PRINA MELLO, ADRIELE; VOLKOV, YURI; CORVIN, AIDEN; TROPEA, DANIELA (2014)Description of novel nanotechnologies to deliver a translational bridge between basic and clinical neuroscience research. • Evaluation of novel in vitro and in vivo nanodiagnostic tools for neuroimaging and the ... -
Nanotoxicity in cancer research: technical protocols and tips considerations for the use of 3D tumour spheroids
MOVIA, DANIA; PRINA MELLO, ADRIELE (InTech, 2018)The poor clinical translation of oncological nanomedicine products is one of the greatest challenges faced by research today. The use of reductionist in vitro models of human cancer and non-predictive animal models is ... -
Proinflammatory Effects of Pyrogenic and Precipitated Amorphous Silica Nanoparticles in Innate Immunity Cells.
PRINA MELLO, ADRIELE; MOVIA, DANIA (2016)Amorphous silica nanoparticles (ASNP) can be synthetized via several processes, 2 of which are the thermal route (to yield pyrogenic silica) and the wet route from a solution containing silicate salts (to obtain precipitated, ... -
The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure
PRINA MELLO, ADRIELE; MARTIN-LOECHES, IGNACIO (Springer Paris, 2017)Background Pre-evaluation of endogenous immunoglobulin levels is a potential strategy to improve the results of intravenous immunoglobulins in sepsis, but more work has to be done to identify those patients who could ... -
Reexamination of magnetic isotope and field effects on adenosine triphosphate production by creatine kinase
COEY, JOHN MICHAEL DAVID; PRINA MELLO, ADRIELE (2012)The influence of isotopically enriched magnesium on the creatine kinase catalyzed phosphorylation of adenosine diphosphate is examined in two independent series of experiments where adenosine triphosphate (ATP) concentrations ... -
RSOS submission raw data
PRINA MELLO, ADRIELE (RSOS, 2017) -
Targeted polyethylene glycol gold nanoparticles for the treatment of pancreatic cancer: from synthesis to proof-of-concept in vitro studies.
MOVIA, DANIA; VOLKOV, YURI; PRINA MELLO, ADRIELE; MAGUIRE, CIARAN (2016)Abstract: The main objective of this study was to optimize and characterize a drug delivery carrier for doxorubicin, intended to be intravenously administered, capable of improving the therapeutic index of the chemotherapeutic ... -
Theoretical modelling of physiologically stretched vessel in magnetisable stent assisted magnetic drug targeting application
PRINA MELLO, ADRIELE (2010)The magnetisable stent assisted magnetic targeted drug delivery system in a physiologically stretched vessel is considered theoretically. The changes in the mechanical behaviour of the vessel are analysed under the influence ... -
Towards a nanospecific approach for risk assessment.
MOVIA, DANIA; PRINA MELLO, ADRIELE (2016)In the current paper, a new strategy for risk assessment of nanomaterials is described, which builds upon previous project outcomes and is developed within the FP7 NANoREG project. NANoREG has the aim to develop, for the ...