Browsing by Author "MORRIS, DEREK WILLIAMS"
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An assessment of the Irish population for large-scale genetic mapping studies involving epilepsy and other complex diseases
CORVIN, AIDEN; GILL, MICHAEL; MORRIS, DEREK WILLIAMS; O'DUSHLAINE, COLM (Nature Publishing Group, 2008)The recent completion of the International HapMap Project has rapidly advanced our understanding of linkage disequilibrium (LD) in the human genome. Today, tagging SNPs (tSNPs) can be quickly and easily selected and ... -
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.
CORVIN, AIDEN; GILL, MICHAEL; MORRIS, DEREK WILLIAMS (Nature Publishing Group, 2008)To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 10-9) in ANK3 (ankyrin G). We also ... -
Do antisaccade deficits in schizophrenia provide evidence of a specific inhibitory function?
GARAVAN, HUGH PATRICK; ROBERTSON, IAN; CORVIN, AIDEN PETER; MORRIS, DEREK WILLIAMS; DONOHOE, GARY (JAMES) (Cambridge University Press, 2006)Background: Despite its inhibitory control requirements, antisaccade deficits have been consistently associated with working memory impairments in schizophrenia. We investigated whether variance in antisaccade per formance ...