Browsing by Author "MORAN, BARRY"
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Alveolar Macrophages Contribute to Respiratory Tolerance by Inducing FoxP3 Expression in Naive T Cells MILLS, KINGSTON; KEANE, JOSEPH; RUANE, DARREN; COLEMAN, MICHELLE; MORAN, BARRY (2013)Alveolar macrophages (AMs) from mice and humans have long been known to contribute to maintaining tolerance in the lung. Studies have shown that AMs can induce anergy in CD4+ T cells. Nitric oxide, prostaglandins, and ...
Blocking retinoic acid receptor-α enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells GALVIN, KAREN; HIGGINS, SARAH; MILLS, KINGSTON; STEFANSKA, ANNA; MORAN, BARRY; DUNGAN, LARA (2013)The immune system has evolved regulatory mechanisms to control immune responses to self-antigens. Regulatory T (Treg) cells play a pivotal role in maintaining immune tolerance, but tumour growth is associated with local ...
CD11c+CD8alpha+ dendritic cells promote protective immunity to respiratory infection with Bordetella pertussis. MILLS, KINGSTON; MORAN, BARRY (The American Association of Immunologists, 2009)CD11c+CD8?+ and CD103+ DC have been shown to promote regulatory T cell responses and mediate tolerance in the gastrointestinal tract. These cells have also been identified in the lung, but their role in immunity to ...
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-beta MORAN, BARRY; MILLS, KINGSTON; FLETCHER, JEAN (2008)
Immune dysfunction in the skin disease hidradenitis suppurativa MORAN, BARRY (Trinity College Dublin. School of Biochemistry & Immunology. Discipline of Biochemistry, 2020)Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease. Painful lesions and boils present at hair follicles of the inframammary fold, genitals, groin, buttocks and perianal areas. Severe cases ...
Remote access technology offers tremendous possibilities to the cytometry community. MORAN, BARRY (2013)