Browsing by Author "Kirca, Murat"
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Barrett's oesophagus and associated cancer : the influence of bile acid regulated genetic factors and intestinal transcription factors in the pathogenesis
Kirca, Murat (Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2012)Gastrooesophageal reflux disease (GORD) is very common and it is estimated that up to 20% of the western population will experience weekly heartburn. The initial simple mucosal damage can lead to further complications like ... -
siRNA Library Screening Identifies a Druggable Immune-Signature Driving Esophageal Adenocarcinoma Cell Growth
Reynolds, John; Long, Aideen; Duggan, Shane P.; Garry, Catherine; Behan, Fiona; Phipps, Sinead; Kudo, Hiromi; Kirca, Murat; Zaheer, Abdul; McGarrigle, Sarah; Goldin, Robert; Kalloger, Steve E.; Schaeffer, David F.; Strid, Jessica; Kelleher, Dermot (2018)This study de fi nes immune-associated factors supportive of esophageal adenocarcinoma cell growth through small interfering RNA screening and pathologic and functional studies. Fostamatinib R788, targeting Janus ...