Browsing by Author "GARAVAN, HUGH"
Now showing items 1-16 of 16
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Aversive learning in adolescents: modulation by amygdala-prefrontal and amygdala-hippocampal connectivity and neuroticism.
GARAVAN, HUGH (2014)Neuroticism involves a tendency for enhanced emotional and cognitive processing of negative affective stimuli and a propensity to worry and be anxious. It is known that this trait modulates fear learning and the activation ... -
Decreased frontal, striatal and cerebellar activation in adults with ADHD during an adaptive delay discounting task
WHELAN, ROBERT; GARAVAN, HUGH; O'CONNELL, REDMOND (2015)An important characteristic of childhood attention-deficit/hyperactivity disorder (ADHD) is a bias towards small immediate versus larger delayed rewards, but it is not known if this symptom is also a feature of adult ADHD. ... -
Dissociated grey matter changes with prolonged addiction and extended abstinence in cocaine users
GARAVAN, HUGH (Public Library of Science, 2013)Extensive evidence indicates that current and recently abstinent cocaine abusers compared to drug-naïve controls have decreased grey matter in regions such as the anterior cingulate, lateral prefrontal and insular cortex. ... -
Early Visual Processing Deficits in Dysbindin-Associated Schizophrenia
ROBERTSON, IAN; GILL, MICHAEL; MORRIS, DEREK; GARAVAN, HUGH; CORVIN, AIDEN; FOXE, JOHN (2008)Background: Variation at the dysbindin gene (DTNBP1) has been associated with increased risk for schizophrenia in numerous independent samples and recently with deficits in general and domain-specific cognitive processing. ... -
Evidence of increased activation underlying cognitive control in ecstasy and cannabis users
ROBERTS, GLORIA; GARAVAN, HUGH (2010)Evidence suggests that users of ecstasy (3,4-methylenedioxymethamphetamine) have behavioural and cognitive deficits and show increased impulsivity. Impulse control impairments have been shown to be common to a number of ... -
fMRI activation during response inhibition and error processing: the role of the DAT1 gene in typically developing adolescents and those diagnosed with ADHD
JOHNSON, KATHERINE; BARRY, EDWINA; ROBERTSON, IAN; GARAVAN, HUGH; HAWI, ZIARIH; MULLIGAN, AISLING; GILL, MICHAEL (2011)The DAT1 gene codes for the dopamine transporter, which clears dopamine from the synaptic cleft, and a variant of this gene has previously been associated with compromised response inhibition in both healthy and clinical ... -
Functional developmental changes underlying response inhibition and error-detection processes
ROBERTSON, IAN; GARAVAN, HUGH; JOHNSON, KATHERINE (2009) -
Global genetic variations predict brain response to faces.
GARAVAN, HUGH (2014)Face expressions are a rich source of social signals. Here we estimated the proportion of phenotypic variance in the brain response to facial expressions explained by common genetic variance captured by ∼ 500,000 single ... -
Incomplete Hippocampal Inversion: A Comprehensive MRI Study of Over 2000 Subjects.
BOKDE, ARUN; GARAVAN, HUGH; WHELAN, ROBERT (2015)The incomplete-hippocampal-inversion (IHI), also known as malrotation, is an atypical anatomical pattern of the hippocampus, which has been reported in healthy subjects in different studies. However, extensive characterization ... -
Menstrual cycle phase modulates cognitive control over male but not female stimuli
GARAVAN, HUGH; NEWELL, FIONA (2008)Evolutionary selection pressures have been one of the factors proposed to underlie sex differences in inhibitory control. Consequently, inhibitory control may vary as a function of the menstrual cycle and may be modulated ... -
A phenotypic structure and neural correlates of compulsive behaviors in adolescents.
GARAVAN, HUGH; WHELAN, ROBERT (2013)BACKGROUND: A compulsivity spectrum has been hypothesized to exist across Obsessive-Compulsive disorder (OCD), Eating Disorders (ED), substance abuse (SA) and binge-drinking (BD). The objective was to examine the validity ... -
Positive association of video game playing with left frontal cortical thickness in adolescents.
GARAVAN, HUGH (2014)Playing video games is a common recreational activity of adolescents. Recent research associated frequent video game playing with improvements in cognitive functions. Improvements in cognition have been related to grey ... -
Randomized parcellation based inference
BOKDE, ARUN; GARAVAN, HUGH (2014)29 Accepted 5 November 2013 30 Available online xxxx 3213 34 Keywords: 35 Group analysis 36 Parcellation 37 Reproducibility 38 Multiple comparisons 39 Permutations 54 53 55 Introduction 56 Analysis of brain ... -
Resting-state connectivity deficits associated with impaired inhibitory control in non-treatment-seeking adolescents with psychotic symptoms
GARAVAN, HUGH; DONOHOE, GARY (2014)Objective— Psychotic symptoms are common in the population and index risk for a range of severe psychopathological outcomes. We wished to investigate functional connectivity in a community sample of adolescents who ... -
A review of neuropsychological and neuroimaging research in autistic spectrum disorders: Attention, inhibition and cognitive flexibility
GARAVAN, HUGH; MCGRATH, JANE (2008)Autistic spectrum disorders (ASD) are devastating neurodevelopmental disorders of unknown aetiology with characteristic deficits in social interaction, communication and behaviour. Individuals with ASD show deficits in ... -
White-matter microstructure and gray-matter volumes in adolescents with subthreshold bipolar symptoms
GARAVAN, HUGH (2014)Abnormalities in white-matter (WM) microstructure, as lower fractional anisotropy (FA), have been reported in adolescent-onset bipolar disorder and in youth at familial risk for bipolarity. We sought to determine whether ...