Browsing by Author "Callaghan, Susan"

Now showing items 1-6 of 6

    • BODIPY-Pyrene and Perylene Dyads as Heavy-Atom-Free Singlet Oxygen Sensitizer 

      Senge, Mathias; Filatov, Mikhail A.; Karuthedath, Safakath; Polestshuk, Pavel M.; Callaghan, Susan; Flanagan, Keith J.; Wiesner, Thomas; Laquai, Frédéric (2018)
      Dyads combining BODIPY as an electron acceptor and pyrene or perylene as electron donor subunits were prepared and their photophysical properties were studied by steady‐state and transient spectroscopy. Depending on the ...

    • Delayed release singlet oxygen sensitizers based on pyridone-appended porphyrins 

      Senge, Mathias; Callaghan, Susan; Filatov, Mikhail A.; Sitte, Elisabeth; Savoie, Huguette; Boyle, Ross W.; Flanagan, Keith J. (2017)
      A new type of porphyrin photosensitizer capable of generating singlet oxygen upon irradiation, storing it through binding to pyridone subunits, followed by slow release at 20‐40 °C is reported. The timescale of singlet ...

    • In vitro cytotoxicity of a library of BODIPY-anthracene and -pyrene dyads for application in photodynamic therapy 

      Senge, Mathias; Callaghan, Susan; Filatov, Mikhail A.; Savoie, Huguette; Boyle, Ross W. (2019)
      The facile synthesis and in vitro activity of a library of heavy atom-free BODIPY-anthracene, -pyrene dyads (BAD-13–BPyrD-19) and a control (BODIPY 20) are reported. We demonstrate that singlet oxygen produced from dyad ...

    • A lead BODIPY-phenylanthracene dyad for application in photodynamic therapy 

      Senge, Mathias; Callaghan, Susan; Filatov, Mikhail A.; Savoie, Huguette; Boyle, Ross W. (2019)
      Over the past four years we have developed BODIPY dyads capable of triplet state generation from a charge transfer states generated by photoinduced electron transfer. In the current work we identify a lead compound for ...

    • New Materials for Controlled Singlet Oxygen Generation 

      Callaghan, Susan (Trinity College Dublin. School of Chemistry. Discipline of Chemistry, 2021)
      Singlet oxygen is notoriously uncontrollable, suffers from poor selectivity, and has fast decomposition rates in biological media. Across the scientific community, there is an enduring effort to refine singlet oxygen ...

    • Structural, Photophysical, and Photobiological Studies on BODIPY-Anthracene Dyads 

      Senge, Mathias; Flanagan, Keith J.; Callaghan, Susan (2021)
      We report the structural, photophysical, and photobiological properties of a promising BODIPY-anthracene dyad (BAD) that was previously shown to i nduce a therapeutic effect against MDA-MB-468 cells. The BODIPY was ...