Browsing by Author "CAMPBELL, MATTHEW"
Now showing items 1-13 of 13
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Blood-brain barrier regulation in psychiatric disorders
CAMPBELL, MATTHEW (2018) -
Endogenous oils derived from human adipocytes are potent adjuvants that promote IL-1 alpha-dependent inflammation.
O'FARRELLY, CLIONA; LAVELLE, EDWARD; CAMPBELL, MATTHEW; MOK, KENNETH (2014)Obesity is characterized by chronic inflammation associated with neutrophil and M1 macrophage infiltration into white adipose tissue. However, the mechanisms underlying this process remain largely unknown. Based on the ... -
Enhancement of outflow facility in the murine eye by targeting selected tight-junctions of Schlemm's canal endothelia
HUMPHRIES, PETER; CAMPBELL, MATTHEW; HUMPHRIES, MARIAN (2017)The juxtacanalicular connective tissue of the trabecular meshwork together with inner wall endothelium of Schlemm’s canal (SC) provide the bulk of resistance to aqueous outflow from the anterior chamber. Endothelial cells ... -
First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models.
WALSH, CATHAL; TIPTON, KEITH; KELLY, JULIE; HARDIMAN, ORLA; O'MARA, SHANE; CAMPBELL, MATTHEW; VAJDA, ALICE; GOBBO, OLIVIERO (2015) -
GlycoRDF: An ontology to standardize glycomics data in RDF
CAMPBELL, MATTHEW (2015)Motivation: Over the last decades several glycomics-based bioinformatics resources and databases have been created and released to the public. Unfortunately, there is no common standard in the representation of the stored ... -
Manipulating ocular endothelial tight junctions: Applications in treatment of retinal disease pathology and ocular hypertension
HUMPHRIES, PETER; CAMPBELL, MATTHEW (2018) -
MDMA "ecstasy' increases cerebral cortical perfusion determined by bolus-tracking arterial spin labelling (btASL) MRI
CAMPBELL, MATTHEW; KERSKENS, CHRISTIAN; CAMPBELL, MATTHEW; KERSKENS, CHRISTIAN MATTHIAS (2013)BACKGROUND AND PURPOSE: The purpose of this study was to assess cerebral perfusion changes following systemic administration of the recreational drug 3,4-methylendioxymethamphetamine (MDMA 'ecstasy') to rats. EXPERIMENTAL ... -
Targeting the NLRP3 inflammasome in chronic inflammatory diseases: Current perspectives
CAMPBELL, MATTHEW; DOYLE, SARAH (2015)The inflammasome is a molecular platform formed by activation of an innate immune pattern recognition receptor seed, such as NLRP3. Once activated, NLRP3 recruits the adapter ASC (apoptosis-related speck-like protein ...