Browsing by Author "ROWAN, MICHAEL JOSEPH"
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Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity
ROWAN, MICHAEL JOSEPH; ANWYL, ROGER; WANG, QIN-WEN (Oxford University Press, 2008)Non-steroidal anti-inflammatory agents (NSAIDs) are associated with a marked reduction in the risk of developing Alzheimer's disease, a form of dementia characterized by the accumulation of amyloid plaques containing the ... -
Protection against ß-amyloid-induced synaptic and memory impairments via altering ß-amyloid assembly by bis(heptyl)-cognitin
ROWAN, MICHAEL; ANWYL, ROGER; ROWAN, MICHAEL JOSEPH; ANWYL, ROGER (2015)β-amyloid (Aβ) oligomers have been closely implicated in the pathogenesis of Alzheimer’s disease (AD). We found, for the first time, that bis(heptyl)-cognitin, a novel dimeric acetylcholinesterase (AChE) inhibitor derived ...