Browsing by Author "GARAVAN, HUGH PATRICK"
Now showing items 21-40 of 51
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A functional MRI study of the influence of practice on component processes of working memory.
GARAVAN, HUGH PATRICK (Elsevier, 2004)Previous neuroimaging studies have shown that neural activity changes with task practice. The types of changes reported have been inconsistent, however, and the neural mechanisms involved remain unclear. In this study, we ... -
Human functional neuroimaging of brain changes associated with practice
GARAVAN, HUGH PATRICK (Oxford University Press, 2005)The discovery that experience-driven changes in the human brain can occur from a neural to a cortical level throughout the lifespan has stimulated a proliferation of research into how neural function changes in response ... -
Increased ventral striatal BOLD activity during non-drug reward anticipation in cannabis users
GARAVAN, HUGH PATRICK (2010)Despite an increased understanding of the pharmacology and long-term cognitive effects of cannabis in humans, there has been no research to date examining its chronic effects upon reward processing in the brain. Motivational ... -
Individual differences in error processing: A review and reanalysis of three event-related fMRI studies using the GO/NOGO task
GARAVAN, HUGH PATRICK (Oxford University Press, 2004)Three previous studies using the GO/NOGO task were examined to characterize the pattern of functional activation seen during error-related processing. The large sample size (n = 44) also allowed investigation of the influence ... -
Individual differences in the neuroanatomy of inhibitory control
GARAVAN, HUGH PATRICK (Elsevier, 2006)We combined the data of five event-related fMRI studies of response inhibition. The re-analysis (n = 71) revealed response inhibition to be accomplished by a largely right hemisphere network of prefrontal, parietal, ... -
The Irish mind abroad - the experiences and attitudes of the Irish diaspora
GARAVAN, HUGH PATRICK (The Psychological Society of Ireland, 1994) -
Learning and memory deficits in ecstasy users and their neural correlates during a face-learning task
GARAVAN, HUGH PATRICK; ROBERTS, GLORIA (Elsevier, 2009)It has been consistently shown that ecstasy users display impairments in learning and memory performance. In addition, working memory processing in ecstasy users has been shown to be associated with neural alterations in ... -
Loss of insight in frontotemporal dementia, corticobasal degeneration and progressive supranuclear palsy
GARAVAN, HUGH PATRICK (Oxford University Press, 2007)Loss of insight is one of the core features of frontal/behavioural variant frontotemporal dementia (FTD). FTD shares many clinical and pathological features with corticobasal degeneration (CBD) and progressive supranuclear ... -
Multiple neuronal networks mediate sustained attention
GARAVAN, HUGH PATRICK (MIT Press, 2003)& Sustained attention def icits occur i n several neuropsychi- atric di sorders. However, the underlying neurobiol ogical mechani sms are stil l i ncompletely understood. To that end, f unctional MRI was used to ... -
The neural basis of video gaming
GARAVAN, HUGH PATRICK (2011)Video game playing is a frequent recreational activity. Previous studies have reported an involvement of dopamine-related ventral striatum. However, structural brain correlates of video game playing have not been investigated. ... -
Neural mechanisms for response selection: comparing selection of items and responses from working memory.
GARAVAN, HUGH PATRICK (Elsevier, 2007)Recent functional imaging studies of working memory (WM) have suggested a relationship between the requirement for response selection and activity in dorsolateral prefrontal (DLPFC) and parietal regions. Although a number ... -
Neural mechanisms involved in error processing: A comparison of errors made with and without awareness
GARAVAN, HUGH PATRICK (Elsevier, 2005)The ability to detect an error in one's own performance and then to improve ongoing performance based on this error processing is critical for effective behaviour. In our event-related fMRI experiment, we show that explicit ... -
The NOS1 variant rs6490121 is associated with variation in prefrontal function and gray matter density in healthy individuals
FRODL, THOMAS; DONOHOE, GARY (JAMES); GILL, MICHAEL; CORVIN, AIDEN PETER; NEWELL, FIONA; ROSE, EMMA; FAHEY, CIARA; GARAVAN, HUGH PATRICK; BOKDE, ARUN LAWRENCE WARREN; O'DOHERTY, JOHN PHILIP; MC GRATH, JANE; KELLY, SINEAD; ROBERTSON, IAN H; MORRIS, DEREK (Elsevier, 2012)A common polymorphism within the nitric oxide sythanse-1 (NOS1) gene (rs6490121), initially identified as risk variant for schizophrenia, has been associated with variation in working memory and IQ. Here we investigated ... -
A paramatric manipulation of central executive functioning
GARAVAN, HUGH PATRICK (Oxford University Press, 2000)The central executive is both an important and poorly understood construct that is invoked in current theoretical models of human cognition and in various dysexecutive clinical syndromes. We report a task designed to isolate ... -
A pattern recognition approach to the detection of single-trial event-related fMRI.
GARAVAN, HUGH PATRICK (IFMBE, 2004)Functional magnetic resonance imaging (FMRI) is an imaging technique for determining which regions of the brain are activated in response to a stimulus or event. Early FMRI experiment paradigms were based upon those ... -
Patterns of normal human brain plasticity and their implications for neurorehabilitation.
GARAVAN, HUGH PATRICK (Elsevier, 2006)Patterns of normal human brain plasticity after practice and their implications for neurorehabilitation. -
Post-error behaviour in active cocaine users: poor awareness of errors in the presence of intact performance adjustments.
GARAVAN, HUGH PATRICK (Nature, 2007)Active cocaine abusers have a diminished neural response to errors, particularly in the anterior cingulate cortex thought critical to error processing. The inability to detect, or adjust performance following errors has ... -
Predicting success: The effect of pre-target cueing on inhibition performance.
GARAVAN, HUGH PATRICK (MIT Press, 2004)The present study investigated the relationships between attention and other preparatory processes prior to a response inhibition task and the processes involved in the inhibition itself. To achieve this, a mixed ... -
Prefrontal and midline interactions mediating behavioural control.
GARAVAN, HUGH PATRICK (Blackwell, 2009)Top-down control processes are thought to interact with bottom-up stimulus-driven task demands to facilitate the smooth execution of behaviour. Frontal and midline brain areas in humans are believed to subserve these control ... -
Reduced striatal volume in cocaine-dependent patients
GARAVAN, HUGH PATRICK (2011)Long-term cocaine consumption is associated with brain structural and functional changes. While the animal literature on cocaine use and dependence has traditionally focused on the striatum, previous human studies using ...