Yuan L., Zheng, Y.F., Chen. W., and Caffrey, M., Automatic Mixing of Bio-Samples Using Micro-Channel and Centrifugation, Proc. IEEE Conference on Automation Science and Engineering,, IEEE Conference on Automation Science and Engineering,, Scottsdale, AZ, September 22-25, IEEE, 2007, 634-639
Automatic mixing of bio-samples using micro-channel and centrifugation is considered. Existing methods for mixing bio-samples for life science applications use micro-well and micro-stirrer which are ineffective when used with highly viscous materials at the microliter or nanoliter level. Our method mixes viscous bio-samples in micro-capsules using micro-channel and centrifugation which minimizes contact with mixing tools. To introduce the method, firstly the design of the micro-capsule along with the micro-channel is presented. Secondly, a hydrodynamic model describing the flow of viscous materials in the micro-channel is presented, and the average sample velocity and the traveling time through the micro-channel are analyzed. Thirdly, the relationship between centrifugation speed and time is given to achieve effective and efficient control of the flow. Finally, experimental and theoretical results are compared.
Please note: There is a known bug in some browsers that causes an
error when a user tries to view large pdf file within the browser window.
If you receive the message "The file is damaged and could not be
repaired", please try one of the solutions linked below based on the
browser you are using.
Items in TARA are protected by copyright, with all rights reserved, unless otherwise indicated.