The University of Dublin | Trinity College -- Ollscoil Átha Cliath | Coláiste na Tríonóide
Trinity's Access to Research Archive
Home :: Log In :: Submit :: Alerts ::

TARA >
School of Medicine >
Psychiatry >
Psychiatry (Scholarly Publications) >

Please use this identifier to cite or link to this item: http://hdl.handle.net/2262/41035

Title: The Psychosis Susceptibility gene ZNF804A: associations, functions and phenotypes
Author: CORVIN, AIDEN PETER
DONOHOE, GARY (JAMES)
MORRIS, DEREK
Sponsor: Science Foundation Ireland
Health Research Board
Author's Homepage: http://people.tcd.ie/acorvin
http://people.tcd.ie/donoghug
http://people.tcd.ie/morrisdw
Keywords: ZNF804A
genetics
cognition
imaging
Issue Date: 2010
Citation: Donohoe G, Morris DW, Corvin A, The Psychosis Susceptibility gene ZNF804A: associations, functions and phenotypes, Schizophrenia Bulletin, 36, 5, 2010, 904-909
Series/Report no.: Schizophrenia Bulletin
36
5
Abstract: As the first gene to have achieved genome-wide significance for psychosis, ZNF804A has predictably been a subject of intense research activity. We review the evidence to date for the association between schizophrenia and the original risk variant rs1344706 identified as well as additional common and rare variants at this locus. We describe the still scant literature on the biological function of ZNF804A and discuss the efforts being made to characterize and refine the associated phenotype using imaging and neuropsychological approaches. We conclude that ZNF804A is robustly, if modestly, associated with schizophrenia risk, with much work still remaining to elucidate its role in schizophrenia biology.
Description: PUBLISHED
URI: http://hdl.handle.net/2262/41035
Related links: http://dx.doi.org/10.1093/schbul/sbq080
Appears in Collections:Psychiatry (Scholarly Publications)

Files in This Item:

File Description SizeFormat
ZNF_review_SZ Bull_Final.docAccepted for publication (author's copy) - Peer Reviewed79.5 kBMicrosoft WordView/Open
The Psychosis Susceptibility Gene ZNF804A- Associations, Functions, and Phenotypes.pdfpublished (publisher copy) peer-reviewed76.18 kBAdobe PDFView/Open


This item is protected by original copyright


Please note: There is a known bug in some browsers that causes an error when a user tries to view large pdf file within the browser window. If you receive the message "The file is damaged and could not be repaired", please try one of the solutions linked below based on the browser you are using.

Items in TARA are protected by copyright, with all rights reserved, unless otherwise indicated.

 

Valid XHTML 1.0! DSpace Software Copyright © 2002-2010  Duraspace - Feedback