Vittoria Flamini, Christian Kerskens, Kevin Mattheus Moerman, Ciaran Simms and Caitríona Lally, Imaging Arterial Fibres Using Diffusion Tensor Imaging Feasibility Study and Preliminary Results, EURASIP Journal on Advances in Signal Processing, 2010, 904091, 2010
EURASIP Journal on Advances in Signal Processing 2010 904091
MR diffusion tensor imaging (DTI) was used to analyze the fibrous structure of aortic tissue. A fresh porcine aorta was imaged at 7T using a spin echo sequence with the following parameters: matrix 128 x 128 pixel; slice thickness 0.5 mm; interslice spacing 0.1 mm; number of slices 16; echo time 20.3 s; field of view 28 mm x 28 mm. Eigenvectors from the diffusion tensor images were calculated for the central image slice and the averaged tensors and the eigenvector corresponding to the largest eigenvalue showed two distinct angles corresponding to near 0 degrees and 180 degrees to the transverse plane of the aorta. Fibre tractography within the aortic volume imaged confirmed that fibre angles were oriented helically with lead angles of 15 +/- 2.5 degrees and 175 +/- 2.5 degrees. The findings correspond to current histological and microscopy data on the fibrous structure of aortic tissue, and therefore the eigenvector maps and fibre tractography appear to reflect the alignment of the fibers in the aorta. In view of current efforts to develop noninvasive diagnostic tools for cardiovascular diseases, DTI may offer a technique to assess the structural properties of arterial tissue and hence any changes or degradation in arterial tissue.
Please note: There is a known bug in some browsers that causes an
error when a user tries to view large pdf file within the browser window.
If you receive the message "The file is damaged and could not be
repaired", please try one of the solutions linked below based on the
browser you are using.
Items in TARA are protected by copyright, with all rights reserved, unless otherwise indicated.