Raman Parkesh, T. Clive Lee and Thorfinnur Gunnlaugsson, Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors, Tetrahedron Letters, 50, 28, 2009, 4114-4116
Tetrahedron Letters 50 28
The ability of two 4-amino-1,8-naphthalimides (1 and 2) and anthracene (3) based photoinduced electron transfer (PET) sensors, previously developed in our laboratory, to function as selective imaging agents for exposed Ca(II) in bone cracks, using fluorescence microscopy imaging is described. While the emission from 3 is masked by the autofluorescence arising from the (bovine) bone matrix, both 1 and 2, emitting in the green, are able to clearly identify areas of damaged bone.
Please note: There is a known bug in some browsers that causes an
error when a user tries to view large pdf file within the browser window.
If you receive the message "The file is damaged and could not be
repaired", please try one of the solutions linked below based on the
browser you are using.
Items in TARA are protected by copyright, with all rights reserved, unless otherwise indicated.