TARA: Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors

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Please use this identifier to cite or link to this item: http://hdl.handle.net/2262/39290

Title:	Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors
Author:	GUNNLAUGSSON, THORFINNUR
Sponsor:	Health Research Board
Author's Homepage:	http://people.tcd.ie/gunnlaut
Keywords:	Chemistry
Issue Date:	2009
Publisher:	Elsevier
Citation:	Raman Parkesh, T. Clive Lee and Thorfinnur Gunnlaugsson, Fluorescence imaging of bone cracks (microdamage) using visibly emitting 1,8-naphthalimide-based PET sensors, Tetrahedron Letters, 50, 28, 2009, 4114-4116
Series/Report no.:	Tetrahedron Letters 50 28
Abstract:	The ability of two 4-amino-1,8-naphthalimides (1 and 2) and anthracene (3) based photoinduced electron transfer (PET) sensors, previously developed in our laboratory, to function as selective imaging agents for exposed Ca(II) in bone cracks, using fluorescence microscopy imaging is described. While the emission from 3 is masked by the autofluorescence arising from the (bovine) bone matrix, both 1 and 2, emitting in the green, are able to clearly identify areas of damaged bone.
Description:	PUBLISHED
URI:	http://hdl.handle.net/2262/39290
Related links:	http://dx.doi.org/10.1016/j.tetlet.2009.04.115
Appears in Collections:	Chemistry (Scholarly Publications)

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